Skin Allergy

Atopic eczema, also known as eczema or atopic dermatitis, is an inflammatory, chronically relapsing, pruritic skin disease. It is one of the commonest dermatoses. 2.5% of adults in the UK and up to 4.9% of adults globally report doctor-diagnosed eczema.1 It affects up to an estimated 16% of children in the UK and 7-8% globally.2 affects both sexes with a slight male predominance.

The association with atopy differentiates atopic eczema from eczema associated with irritants, allergic contact, discoid, venous, seborrhoeic and photosensitivity, which have different disease patterns and aetiologies.

A complex interaction of genetics and environment all contribute to the overall clinical picture.

The key pathophysiological features of atopic eczema are dysfunction of the epidermalĀ barrier and immune-mediated inflammation.

 

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