This is a two centre study (Cambridge and Imperial). A study of 4 peanut challenges in each of 65 adult peanut allergic patients. The objectives are to define the peanut reactive threshold in UK patients for the first time, and to define the effects of two co-factors (stress and exercise) on the threshold and severity of reactions. Each patients undergoes two baseline peanut challenges to model the population and intra-individual variability in threshold. Each patient also undergoes two peanut challenges with co-factors (sleep deprivation and exercise).
A study of 4 peanut challenges in 65 adult peanut allergic patients. The objectives are to define the peanut reactive threshold in UK patients for the first time, and to define the effects of two co-factors (stress and exercise) on the threshold and severity of reactions.
Clinical procedures have been completed. Publication due H1 2017