Egg Allergy 2021 - BSACI

Egg Allergy 2021

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Clinical & Experimental Allergy, Volume 51, Issue 10 p. 1262-1278


This guideline advises on the management of patients with egg allergy. Most commonly egg allergy presents in infancy, with a prevalence of approximately 2% in children and 0.1% in adults. A clear clinical history will confirm the diagnosis in most cases. Investigation by measuring egg specific IgE (by skin prick testing or specific IgE assay) is useful in moderate – severe cases or where there is diagnostic uncertainty. Following an acute allergic reaction, egg avoidance advice should be provided. Egg allergy usually resolves, and re-introduction can be achieved at home if reactions have been mild and there is no asthma. Patients with a history of severe reactions or asthma should have reintroduction guided by a specialist. All children with egg allergy should receive the MMR vaccine. Most adults and children with egg allergy can receive the influenza vaccine in primary care, unless they have had anaphylaxis to egg requiring intensive care support. Yellow Fever vaccines should only be considered in egg allergic patients under the guidance of an allergy specialist. This guideline was prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI) and is intended for allergists and others with a special interest in allergy. The recommendations are evidence-based. Where evidence was lacking, consensus was reached by the panel of specialists on the committee. The document encompasses epidemiology, risk factors, diagnosis, treatment, prognosis, and co-morbid associations.


Food, egg, allergy, anaphylaxis, diagnosis, aetiology, management, adrenaline, epinephrine, BSACI, SOCC


Susan C. Leech, Pamela W. Ewan, Isabel J. Skypala, Nicola Brathwaite, Mich Erlewyn- Lajeunesse, Sarah Heath, Heidi Ball, Polly James, Karen Murphy, Andrew T. Clark.


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